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Source Calcif Tissue Int. 1990 Mar;46(3):189-94
Source link http://www.ncbi.nlm.nih.gov/sites/entrez
Title Bone marrow fat content in relation to bone remodeling and serum chemistry in intact and ovariectomized dogs.
Author Martin RB, Chow BD, Lucas PA.
Bio Orthopaedic Research Laboratory, University of California, Davis 95616. .
Abstract It was previously shown that 11 months after ovariectomy the volume fraction of trabecular bone in the spine and 11th rib medullary canal of Beagle dogs (6 control, 9 ovariectomized) was significantly reduced. In this paper it is shown that these changes are accompanied by increased marrow fat volume in the 11th rib (59.0 +/- 9.5% vs. 44.3 +/- 10.0%). Conversely, the volume fraction of functional (hematopoietic) cells in the marrow was reduced by ovariectomy. Additionally, variations in marrow fat volume were tested for correlation with 22 other variables pertinent to bone physiology. Marrow fat volume was significantly positively correlated with serum osteocalcin, rib trabecular bone porosity, rib cross-sectional area, and gains in body weight. It was negatively correlated with serum estrogen concentrations and the extent of rib trabecular surfaces labeled with tetracycline. PMID: 2106378 [PubMed - indexed for MEDLINE]

 

 This study came from UC Davis, both a veterinary and a medical school. This study showed that in addition to bone mineral and volume depletion, sex hormone loss also depletes bone marrow content. Not having good marrow sets us up for anemia and less immune function. As you will see in other articles in this section, EstraPet can prevent this because of its isoflavone content. Life is so much better for us and our pets (let alone the hassle, expense, and misery) if we keep things running smoothly and prevent many of these problems in the first place. In this regard, EstraPet is revolutionary.
Category BONE / JOINT
Date 3/6/2008 8:56:22 AM